With the aging of the global population and the increasing shortage of medical resources, governments and people around the world are paying more and more attention to the smart medical industry. Smart technology can empower medical care to break through geographical, air, time and resource constraints, and greatly improve the efficiency, efficiency and effectiveness of medical services. Smart medical care is an important direction for the future development of medical care. In an interview with the author, Yu Yigang, application manager of ADI’s medical business system in Asia Pacific, said that the medical equipment industry as a whole has entered a stage of rapid growth, intelligent diagnosis and treatment, intelligent image recognition, intelligent health management related to intelligent wearable devices, and medical robots. It will be the main development direction of applications in the field of medical equipment. The recognition and diagnosis of medical images with artificial intelligence applied; and the use of medical-grade smart wearable devices combined with telemedicine will be the next hot spot.
At present, the global smart medical industry is in a stage of steady development, and the market scale is constantly expanding. According to relevant data, the compound annual growth rate of global smart medical service spending from 2016 to 2018 is about 60%. It is estimated that the global smart medical service industry scale is expected to reach 400 billion US dollars in 2019. Under the huge market situation, companies related to the industry chain have begun to actively seize the market, and the spring of the global smart medical industry is coming. Yu Yigang gave a detailed introduction to ADI’s layout in the medical field. ADI’s technologies and products run through the entire health industry chain, including prevention, diagnosis, treatment, and disease management. There are two main types of applications in medical Electronic monitoring and monitoring: medical image detection and sign signal monitoring.
·Medical image detection
ADI’s high-precision, high-performance, high-reliability sensors, signal processing front-ends and integrated modules in optoelectronics, physiological potential, physiological impedance, motion, body temperature, etc. are all providing reliable medical equipment and wearable devices for vital signal monitoring. Easy to use solution. At the same time, COF (Chip-On-Flex), a high-precision, high-integration analog front-end, also provides a reliable guarantee for the intelligent diagnosis of high-quality medical images of digital flat Panel X-ray machines, CT, and high-end color ultrasound equipment. In addition, ADI’s outstanding technologies and products in power management, signal processing and data communication also provide a complete system-level solution for lower power consumption, smaller size, and remote interconnection required by current and future smart medical devices.
Currently, ADI’s latest generation ADAS1135 is a 256-channel, 24-bit current-to-digital converter module suitable for multi-channel, low-current data acquisition in medical CT (computed tomography), industrial and security scanners, and photodiode sensor applications. The main technical features of the module include: synchronous sampling with no charge loss and no dead time; ultra-low noise; configurable current input range; integrated 2 high-speed ADCs with configurable sampling rates, internal buffers, Decoupling and bypass capacitors; LVDS/CMOS serial interface; on-chip temperature sensor.
The ADAS1135 is packaged in a 15x15mm 324-pin flat SiP BGA package that includes decoupling capacitors for the power supply and reference voltage. The ball grid array is an 18×18 full array, the solder ball pitch is 0.8mm, and the solder ball diameter is 0.45mm. The 0.8mm solder ball spacing enables more wiring between pins, thereby reducing many laser holes and buried holes, improving PCB yield, reliability, and reducing costs. At the same time, a 128-channel version ADAS1134 was launched. In addition, ADI also introduced the ADAS1256 COF (Chip-On-Flex) 256-channel integrated front-end module for digital X-ray. In addition to the single-chip integration of 256 channels, 16-bit resolution, and 22us line scan speed, the ADAS1256 COF solution also provides 9 power consumption modes. As we all know, power consumption and noise cannot meet the minimum requirements at the same time, so the switching function of power consumption mode allows users to choose the best power consumption and noise mode to suit the needs at that time. At the same time, the ADAS1256 COF solution reduces the noise of the detector itself for radiation dose issues such as X-rays that patients are most concerned about, so when the X-ray dose is small, the low-noise detector can also receive and clearly present images.
ADI’s latest generation product, the ADAS1258, has also been introduced, further optimizing speed and power consumption, integrating more system-level functions, and has been tested and developed in final products at key industry customers. In addition, in terms of ultrasonic analog front-end chip solutions, ADI’s related products have been leading the trend of similar products and solutions in the industry. leading position in the field.
·Signal signal monitoring
In addition to the above-mentioned main technologies and products in medical image detection applications, ADI’s products and solutions lead the trend in the monitoring of physical signs, solve the most core problems of users, and obtain considerable market returns, including professional monitoring. Class products (mostly used in hospitals) and wearable products (personal consumer products or personal health products). Specifically, ADI has continued to invest in optoelectronic technology, physiological impedance measurement, physiological potential acquisition, temperature, motion status monitoring, and environmental related (such as gas, CO2 and ultraviolet monitoring, etc.) and product solutions in the market. Approved.
a. In terms of measuring physiological signs by photoelectric method, ADI’s ADPD series sensors and signal processing solutions are being designed and used by almost all major brand customers. ADI’s ADPD series of products with unique advantages, such as ADPD142, ADPD153, ADPD144 and ADPD174, which are specially used in the monitoring of various physiological signs by optoelectronic methods, are currently the most integrated on the market (Photodiode + LED + analog front end using AFE + LED driver + ambient light suppression, etc., the output is the digital quantity of I2C), it is also the smallest in size, the lowest power consumption (very flexible configuration), the best in performance (while the size and power consumption are advantageous) and a very mature Solution (already shipped in large quantities) solution. It can be used for diagnostic-grade products as well as for the collection of relevant signs of consumer-grade products, such as heart rate, blood oxygen content, etc. ADPD188, the latest generation of ADI’s photoelectric measurement module product, further greatly improves the light input efficiency and current conversion ratio (CTR); making this type of application in power consumption, performance, design simplicity, and simplifying customers’ production line processes and costs, etc. Improvements and breakthroughs have been made in this regard.
b. ADI’s family of low-power, single-lead, electrocardiogram ECG analog front ends (AFEs), the AD8233, is designed to meet the ECG signal conditioning requirements of emerging fitness equipment, portable/worn monitoring equipment, and remote health monitoring equipment. Unlike the topologies used in many current integrated solutions, the AD8233’s highly flexible analog filtering configuration uses a bipolar high-pass filter, combined with an on-chip instrumentation amplifier architecture and an unconstrained operational (gain) amplifier, allowing users to use multi-pole low-pass filters. Pass filtering to eliminate line noise and other disturbances, and to provide lead-off monitoring in shutdown mode. It offers system designers flexibility to take fitness and medical monitoring to a new level of value and performance.
c. ADI’s AD5940 analog front-end dedicated to high-precision impedance measurement provides an easy-to-use, one-step solution for body impedance analysis BIA, electrical skin activity EDA/GSR, etc. ADuCM350, a high-precision, low-power on-chip meter that supports a variety of portable healthcare fields, has achieved milestone progress in several representative major domestic and foreign customers. The latest generation has higher precision and lower power consumption. The on-chip meter ADucM355 is also in mass production.
d. The latest generation of high-performance multi-mode sensing front-end ADPD4000 series newly launched by ADI can support PPG, ECG and bio-impedance (Bio-Z) at the same time, and further improve the signal-to-noise ratio and power consumption. The overall wearable solution of performance provides a more convenient design.
e. In terms of body temperature monitoring, ADI’s ADT7422 digital temperature sensor achieves an accuracy of 0.1°C in the body temperature range, a very small package of 4x4mm, and direct digital temperature output. The ADT5912 analog temperature sensor can achieve 0.1°C accuracy from -20°C to 90°C. These temperature sensors can well meet the design of wearable products in terms of small size, high precision, and low power consumption.
f. In the field of motion detection, ADI’s breakthrough ultra-low power 3-axis digital MEMS product ADXL362 consumes only 300nA in motion detection wake-up mode, and its ultra-low power consumption is exactly the feature of wearable motion monitoring equipment. Ideal solution. Similarly, we are interested in the value of low power consumption to users, so similar products with higher performance and more reasonable prices will be launched one after another.
Another highly integrated ADAS1000, provides high-quality and highly integrated multi-lead ECG, respiration and pacemaker detection and other all-in-one solutions, and is the first choice for high-performance diagnostic-grade ECG monitoring.
In addition, as a representative manufacturer of high-performance signal chains, ADI has been committed to providing industry-leading IVD solutions for low-dose, fast, and high-precision in vitro diagnostic instruments. In vitro diagnostic instruments include a variety of different technologies, such as spectroscopic analysis, polymerase chain (PCR), electrochemistry, pH (ISE, pH), liquid level, fluidics and sample processing functions, automatic control and data processing systems, etc. Integration is complex. Among them, optical system control and accuracy are key elements of the system; reagent volume control is important to reduce costs and ensure consistency; measurement speed is very important and sensitive to temperature fluctuations. ADI offers a wide range of amplifiers for I/V conversion, filter design, signal conditioning, and ADC driving, as well as data conversion, signal processing, temperature monitoring, and power management solutions that enable product quality and reliability for in vitro diagnostic instrumentation applications best degree. In addition to in vitro diagnostic instruments, ADI offers a variety of medical and life science instrumentation solutions including infusion pumps, ventilators, anesthesia machines, and more. At the same time, to help customers bring products to market quickly, ADI provides evaluation boards, simulation tools and application expertise to support customers’ design and development efforts.
How do emerging technologies promote smart healthcare?
In recent years, with the development and maturity of AI technologies such as image recognition and natural language processing, as well as emerging technologies such as 5G, Internet of Things, and cloud computing, and with the strong support and encouragement of national policies, the smart medical industry has entered a new era of development.
In this regard, Yu Yigang said that in the era of intelligence, simulation technology is playing an active and key role. In the Global Digital 100 list (Digital 100) released by Forbes, ADI, which is known for its high-performance analog technology, is on the list. With the continuous penetration of intelligence in the medical field, analog signal chain products based on various high-performance sensors are playing an increasingly critical role in the wave of medical intelligence, and analog technology has ushered in a broader space for development. And with the advancement of digital technology, the demand for high-precision, high-speed, low-power analog products continues to expand, and analog products largely determine the performance of today’s digital devices. “The development of industries such as cloud computing, big data, and artificial intelligence is promoting the implementation of medical intelligence. In the era of digital economy with computing power as the core, analog technology and devices play an indispensable role in connecting the real world with A key bridge role in the digital world.
ADI has been deeply involved in the field of medical electronics for decades, and has always deeply integrated leading analog technology with the medical industry. In the face of a new round of technological revolution, relying on its core technology advantages, it insists on responding to the ever-changing industry with innovation. ADI’s above products and solutions are not a single generation of products, but a series of products with strategic planning, the purpose is to lead the market development trend as much as possible, solve the user’s system-level application problems and comprehensively improve the end-user experience. Therefore, we continue to improve performance and cost optimization, thereby consolidating the market position of the double-sided advantage of cost performance. Of course, there are different relative performance comparison conclusions for different application scenarios, specific design goals, and differences in the user’s discriminating conditions. Typically, our new products have at least a 1/3 or more improvement in overall performance over the previous generation, and in most cases we can achieve greater performance. For pioneering products, the performance improvement that can usually help the manufacturer of the whole machine will be more significant. Of course, we usually don’t bring system-level cost increases to users while improving overall performance.
ADI is very optimistic about the prospects of technology and business in the medical field, will continue to focus strategically, and actively participate in relevant seminars and invest in related technology and product development. In fact, ADI’s own medical business team already has biomedical experts to help the entire team provide better solutions to customers. In addition, we have local technical experts who have a deep understanding of medical regulations, and they will work with customers to complete the design challenges of all the specifications in the relevant medical standards in terms of performance and reliability. And a considerable-scale software development team, as well as third-party partners, will provide a full range of solutions for software, hardware and system-level applications.
ADI hopes to help the ultimate patient (or user) and physician to solve the problems they face, such as measurement accuracy, ease of use, cost and reliability, through its own continuous investment, together with our customers. We also hope that with the unremitting efforts of our customers, we can break through the boundaries of existing product forms in terms of business models and product application forms. Challenges such as “distribution of medical resources”, “graded diagnosis and treatment” and “improvement of primary medical facilities” have made their own industry contributions. ADI will continue to work with partners in the whole ecological chain from prevention, diagnosis, treatment, and disease management with an open mind to jointly promote the technological development of China’s medical industry and help to achieve the goal of “Healthy China” of people’s health and longevity.
Current Situation and Challenges of Smart Healthcare
Talking about the development status of China’s medical electronics market and the challenges it faces, Yu Yigang believes that low power consumption, diagnostic-level performance, high integration/small size, and short design cycle are the current challenges in physical signal monitoring equipment. To this end, ADI provides complete system-level solutions and reference designs, and a dedicated technical team provides system-level professional support and technical services. In the medical imaging detection category, such as X-ray flat panel detectors, the design challenges are: lower X-ray dose, fast dynamic images, portability, and reduction of design cycles. The challenges faced by CT are: more layers (16 layers -> 64 layers -> 128 layers -> 320 layers), lower X-ray dose, lower system cost, shorter time to market, etc. ADI provides higher channel count, complete signal chain, lower power consumption, faster, lower noise integrated subsystem, competitive cost and coherent roadmap, with a dedicated team of experts to provide system-level application support, Help customers overcome challenges and accelerate design-to-launch time.
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